How the doses step up

Slowly, each starting on a low dose for 4 weeks. Mounjaro and Zepbound start at 2.5mg a week for 4 weeks, then 5mg, and may go up in 2.5mg steps, at least 4 weeks on each, to as much as 15mg. Wegovy starts at 0.25mg and rises every 4 weeks to 2.4mg from week 17. Your prescriber decides each step.

One step a doseWegovy 7.2mg, if needed

In their own words

Each leaflet’s start and the steps after it, quoted as written.

MedicineStarts onThen
MounjaroThe starting dose is 2.5 mg once a week for four weeks.Mounjaro KwikPen patient leafletAfter four weeks your doctor will increase your dose to 5 mg once a week.Mounjaro KwikPen patient leaflet
ZepboundThe recommended starting dosage is 2.5 mg injected subcutaneously once weekly for 4 weeks.Zepbound prescribing informationIncrease the dosage in 2.5 mg increments after at least 4 weeks until recommended maintenance dosage is achieved.Zepbound prescribing information
WegovyWhen you first start using wegovy®, the starting dose is 0.25 mg once weekly.Wegovy FlexTouch patient leafletYour doctor will instruct you to gradually increase your dose every 4 weeks until you reach the dose of 2.4 mg once weekly.Wegovy FlexTouch patient leaflet
OzempicThe starting dose is 0.25 mg once a week for four weeks.Ozempic patient leafletAfter four weeks your doctor will increase your dose to 0.5 mg once a week.Ozempic patient leaflet

Wegovy, week by week

The table in Wegovy’s leaflet for weight management. 7.2mg is for adults with obesity, if needed, and is three 2.4mg injections on the same day.

WeeksWeekly dose
Weeks 1 to 40.25mg
Weeks 5 to 80.5mg
Weeks 9 to 121mg
Weeks 13 to 161.7mg
From week 172.4mg
From week 217.2mg, if needed

Worth knowing

  • At least 4 weeks a step

    Mounjaro’s leaflet and Zepbound’s label both say at least 4 weeks on one dose before moving to a higher one.

  • Not every step

    Your doctor may go higher if needed, Mounjaro’s says. Zepbound’s weight maintenance doses: 5, 10 or 15mg.

  • Your doctor’s call

    Mounjaro’s and Ozempic’s leaflets say not to change your dose unless your doctor has told you to do so.

Questions

Do I have to go up to the top dose?

Mounjaro’s leaflet says your doctor may increase your dose if you need it, and Zepbound’s label lists 5mg, 10mg or 15mg as maintenance doses for weight reduction. Wegovy’s leaflet steps up to 2.4mg, with 7.2mg only if needed. Your prescriber decides.

Can I go up faster?

Mounjaro and Zepbound say at least 4 weeks on each dose, and Wegovy steps up every 4 weeks. Mounjaro’s and Ozempic’s leaflets say not to change your dose unless your doctor has told you to do so.

What is Wegovy 7.2mg?

A higher dose in Wegovy’s leaflet for adults with obesity, if needed, after at least 4 weeks on 2.4mg. The leaflet says it is three 2.4mg injections, one after another on the same day.

How does Ozempic step up?

From 0.25mg for four weeks to 0.5mg. Its leaflet says your doctor may go to 1mg, then 2mg, if your blood sugar is not controlled well enough on the dose before.

Progress by dose

Jabwise draws your weight across every dose.

Record each new strength and the day you started it. The chart on Progress shades every dose as its own band and runs your weigh-ins across them, since treatment began.

Jabwise Progress: 6.8kg lost over 12 weeks, the weight line drawn across the 2.5mg, 5mg, 7.5mg and 10mg dose bands

Sources

General information, not medical advice. Follow your prescriber’s guidance.

Getting real advice

We’re not doctors. This page sums up what the NHS and the official medicine information say, and can’t tell you what’s right for your body: your prescriber’s instructions and the leaflet in your box come first. More in our terms.

  • Quoted from official sources, each one linked
  • Sources checked 12 October 2026
  • No dosing advice; your prescriber comes first